It's happening again ... again.

Warner Bros. has announced The Hangover III, which will reunite the "Wolfpack" of Bradley Cooper, Ed Helms and Zach Galifianakis with writer/director Todd Phillips for yet another night they'll never almost certainly forget.

The third movie in the billion-dollar comedy franchise will also be its finale, and Phillips says it will be "a fitting conclusion to our three-part opera of mayhem, despair and bad decisions."

The Hangover III begins filming this September, and hits theaters May 24, 2013.

[deadline]