Finding a really good meme is like doing a deep clean of your bedroom and finding a piece of random crap you completely forgot about that brings back sweet memories. That moment of personal recognition is one of those unparalleled feelings that it isn't easy to replicate. Somehow, though, there are memes all over the place that manage to do this for millions of people.
The most important factor in many memes is that we relate to them in some way. Even the more absurd and nonsensical ones often require some sympathetic powers to draw us in. However, apart from that it isn't that complicated to create a meme that will be enjoyed. The rules are open ended, and even when we get it wrong there are those who will enjoy it from an ironic standpoint. We can't lose, so there shouldn't be anything stopping you from looking through a few more of them.