The film is about the thousands of street cats living in Istanbul, the largest city in Turkey, as they have for centuries. Some are wild and fend for themselves, while others are tamer and are cared for by the generosity of people. Kedi depicts these cats, and includes many interviews of the people who interact with them. It focuses on seven of the cats, who are named Sari, Duman, Bengü, Aslan Parçasi, Gamsiz, Psikopat, and Deniz.
The film shows how cats are impacting people in ways only an animal who lives between the worlds of the wild and the tamed can. Cats and their kittens bring joy and purpose to those they choose, giving people an opportunity to reflect on life and their place in it. In Istanbul, cats are the mirrors to ourselves.